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Manufacturer supply top purity (+)-MENTHOL 15356-60-2 with ISO standards
- Molecular Formula: C10H20O
- Molecular Weight: 156.268
- Vapor Pressure: 0.8 mm Hg ( 20 °C)
- Melting Point: 43-44 °C(lit.)
- Refractive Index: 50 ° (C=10, EtOH)
- Boiling Point: 215.383 °C at 760 mmHg
- PKA: 15.30±0.60(Predicted)
- Flash Point: 93.333 °C
- PSA： 20.23000
- Density: 0.89 g/cm3
- LogP: 2.43950
(+)-MENTHOL(Cas 15356-60-2) Usage
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General Description |
(1S,2R,5S)-(+)-menthol is a chiral secondary alcohol. Its alcohol group can be protected as 2-tetrahydrofuranyl ether by reacting with bromotrichloromethane and tetrahydrofuran. |
InChI:InChI=1/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10+/m1/s1
15356-60-2 Relevant articles
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Read,Grubb
, p. 188,193 (1931)
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Enantioselective Hydrolysis of D,L-Menthyl Benzoate to L-(-)-Menthol by Recombinant Candida rugosa Lipase LIP1
Vorlova, Sandra,Bornscheuer, Uwe T.,Gatfield, Ian,Hilmer, Jens-Michael,Bertram, Heinz-Juergen,Schmid, Rolf D.
, p. 1152 - 1155 (2002)
The stereoselective synthesis of L-menth...
Stereoselective reduction of menthone by molecularly imprinted polymers
Hedin-Dahlstroem, Jimmy,Shoravi, Siamak,Wikman, Susanne,Nicholls, Ian A.
, p. 2431 - 2436 (2004)
Polymeric chiral reductants selective fo...
Enantioselective enzymatic resolution of racemic alcohols by lipases in green organic solvents
Belafriekh, Abderahmane,Secundo, Francesco,Serra, Stefano,Djeghaba, Zeineddine
, p. 473 - 478 (2017)
The effects of two eco-friendly solvents...
Apple-tree shoots and transformed carrot and apple roots used as biocatalysts in enantioselective acetate hydrolysis, alcohol oxidation and ketone reduction
Mironowicz, Agnieszka,Kromer, Krystyna
, p. 1655 - 1662 (1998)
(±)-1-Phenylethyl (1), (±)-1-(1-naphthyl...
Novel highly efficient absolute optical resolution method by serial combination of two asymmetric reactions from acetylene monomers having racemic substituents
Aoki, Toshiki,Kaneko, Takashi,Liu, Lijia,Suzuki, Junpei,Tang, Yanan,Teraguchi, Masahiro
supporting information, p. 450 - 461 (2022/01/15)
For general optical resolution, an optic...
Continuous synthesis of menthol from citronellal and citral over Ni-beta-zeolite-sepiolite composite catalyst
Er?nen, Kari,M?ki-Arvela, P?ivi,Martinez-Klimov, Mark,Muller, Joseph,Murzin, Dmitry Yu.,Peurla, Markus,Simakova, Irina,Vajglova, Zuzana
, (2022/04/03)
One-pot continuous synthesis of menthols...
Light-Induced Formation/Scission of C-N, C-O, and C-S Bonds Enables Switchable Stability/Degradability in Covalent Systems
Hai, Yu,Li, Ziyi,Lu, Hanwei,Ye, Hebo,You, Lei,Zou, Hanxun
supporting information, p. 20368 - 20376 (2021/12/03)
The manipulation of covalent bonds could...
Heterogeneous Hydroxyl-Directed Hydrogenation: Control of Diastereoselectivity through Bimetallic Surface Composition
Shumski, Alexander J.,Swann, William A.,Escorcia, Nicole J.,Li, Christina W.
, p. 6128 - 6134 (2021/05/29)
Directed hydrogenation, in which product...
15356-60-2 Process route
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491-07-6,1074-95-9,1196-31-2,3391-87-5,10458-14-7,14073-97-3,18309-28-9,36977-92-1,117773-78-1,89-80-5,17627-49-5,7786-64-3
(+/-)-menthone
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611-70-1
phenyl isopropyl ketone
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611-69-8
rac-2-methyl-1-phenylpropan-1-ol
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89-78-1,490-99-3,491-01-0,491-02-1,1490-04-6,2216-51-5,2216-52-6,3623-51-6,3623-52-7,3623-53-8,15356-60-2,15356-70-4,20747-49-3,20752-33-4,20752-34-5,23283-97-8,64282-88-8
2-isopropyl-5-methylcyclohexan-1-ol
| Conditions | Yield |
|---|---|
|
With
bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum; diisobutylaluminium hydride;
at -78 ℃;
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
|
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108-30-5
succinic acid anhydride
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15356-70-4
menthol
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15356-60-2
(1S,2R,5S)-(+)-menthol
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2216-51-5
(-)-menthol
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77341-67-4
L-menthylsuccinic acid
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204326-53-4
4-((2R,1S,5S)-2-isopropyl-5-methylcyclohexyloxy)-4-oxobutanoic acid
| Conditions | Yield |
|---|---|
|
With
Candida cylindracea lipase;
In
diethyl ether;
at 20 ℃;
for 24h;
Schlenk technique;
Resolution of racemate;
Enzymatic reaction;
|
53 % ee
25 % ee |
15356-60-2 Upstream products
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10458-14-7
(2R,5S)-menthone
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1196-31-2
(1R,4R)-(+)-isomenthone
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15356-70-4
menthol
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10458-14-7
Menthone
15356-60-2 Downstream products
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2085-26-9
di-((1S )-menthyl)-oxalate
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2085-26-9
((1R )-menthyl)-((1S )-menthyl)-oxalate
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149126-05-6
phenylcarbamic acid-((1S )-menthyl ester)
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91796-57-5
4-Methyl-benzenesulfinic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester
