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Cyclohexanone, 4-phenyl-4-(1-piperidinyl)-

  • CAS No.: 65620-13-5
  • Purity: 99%
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Cost-effective and customizable Cyclohexanone, 4-phenyl-4-(1-piperidinyl)- 65620-13-5 in stock

  • Molecular Formula: C17H23NO
  • Molecular Weight: 257.376

65620-13-5 Relevant articles

Discovery of a potent analgesic NOP and opioid receptor agonist: Cebranopadol

Schunk, Stefan,Linz, Klaus,Hinze, Claudia,Frormann, Sven,Oberb?rsch, Stefan,Sundermann, Bernd,Zemolka, Saskia,Englberger, Werner,Germann, Tieno,Christoph, Thomas,K?gel, Babette-Y.,Schr?der, Wolfgang,Harlfinger, Stephanie,Saunders, Derek,Kless, Achim,Schick, Hans,Sonnenschein, Helmut

, p. 857 - 862 (2014/09/29)

In a previous communication, our efforts...

AN EFFICIENT SYNTHESIS OF 1-PHENYL-1-PIPERIDINO-trans-4-METHYLCYCLOHEXANE: UNANTICIPATED TOTAL STEREOSELECTIVITY IN THE CATALYTIC HYDROGENATION OF AN OLEFIN

Vinick, F.J.,Nowakowska, J.,Jung, S.

, p. 741 - 744 (2007/10/02)

A superior synthesis of the title compou...

Phencyclidine compounds and assays for its determination

-

, (2008/06/13)

Novel oxime derivatives of phencyclidine...

65620-13-5 Process route

4-Phenyl-4-piperidinocyclohexanol
60756-83-4

4-Phenyl-4-piperidinocyclohexanol

4-phenyl-4-(1-piperidinyl)cyclohexanone
65620-13-5

4-phenyl-4-(1-piperidinyl)cyclohexanone

Conditions
Conditions Yield
In water; acetic acid;
93%
With jones reagent; sodium citrate; zinc; Yield given. Multistep reaction; 1) acetone;
cyclohexanedione monoethylene ketal
4746-97-8

cyclohexanedione monoethylene ketal

4-phenyl-4-(1-piperidinyl)cyclohexanone
65620-13-5

4-phenyl-4-(1-piperidinyl)cyclohexanone

Conditions
Conditions Yield
Multi-step reaction with 3 steps
1.1: hydrogenchloride / water; methanol / 0 - 20 °C
2.1: tetrahydrofuran / 0 - 20 °C
2.2: 0 - 20 °C
3.1: water; hydrogenchloride / diethyl ether
With hydrogenchloride; water; In tetrahydrofuran; methanol; diethyl ether; water;

65620-13-5 Upstream products

  • 60756-83-4
    60756-83-4

    4-Phenyl-4-piperidinocyclohexanol

  • 4746-97-8
    4746-97-8

    cyclohexanedione monoethylene ketal

  • 155604-21-0
    155604-21-0

    8-Piperidin-1-yl-1,4-dioxa-spiro[4.5]decane-8-carbonitrile

  • 65620-12-4
    65620-12-4

    4-phenyl-4-(1-piperidinyl)cyclohexanone, ethylene ketal hydrochloride

65620-13-5 Downstream products

  • 110915-02-1
    110915-02-1

    1-phenyl-1-piperidino-4-methylenecyclohexane

  • 29084-52-4
    29084-52-4

    trans-Ph/Me 1-(1-phenyl-4-methylcyclohexyl)piperidine

  • 55040-03-4
    55040-03-4

    cis-Ph/Me 1-(1-phenyl-4-methylcyclohexyl)piperidine

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