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Halostachin

  • CAS No.:495-42-1
  • Purity:99%
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Bulk supply high purity Halostachin 495-42-1, Paid sample available

  • Molecular Formula:C9H13NO
  • Molecular Weight:151.208
  • Melting Point:43-45° 
  • Boiling Point:244.1±7.0 °C(Predicted) 
  • PKA:14.03±0.20(Predicted) 
  • PSA:32.26000 
  • Density:1.036±0.06 g/cm3(Predicted) 
  • LogP:1.33030 

Halostachin(Cas 495-42-1) Usage

General Description

Halostachin, also known as 11α, 17α-dihydroxy-9α, 21, 21-trimethyl-19-nor-17β-pregna-1, 4-diene-3, 20-dione, is a synthetic glucocorticoid and a derivative of the natural hormone cortisone. It is used as a pharmaceutical agent for its anti-inflammatory and immunosuppressive properties, making it useful in the treatment of conditions such as asthma, allergic reactions, and autoimmune diseases. Halostachin works by inhibiting the production of inflammatory chemicals in the body, thereby reducing symptoms of inflammation. It is available in various dosage forms, including tablets, injections, and topical preparations, and is typically prescribed by healthcare professionals for short-term use due to its potential side effects and long-term risks.

InChI:InChI=1S/C9H13NO/c1-10-7-9(11)8-5-3-2-4-6-8/h2-6,9-11H,7H2,1H3

495-42-1 Relevant articles

Method for synthesizing chiral alpha-amino alcohol compound

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Paragraph 0026; 0030-0033; 0083-0092, (2021/07/28)

The invention discloses a method for syn...

AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS

-

Page/Page column 83; 84, (2016/07/05)

The present invention is related to amin...

Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors

Langford, H. Marie,Williams, Peter D.,Homnick, Carl F.,Vacca, Joseph P.,Felock, Peter J.,Stillmock, Kara A.,Witmer, Marc V.,Hazuda, Daria J.,Gabryelski, Lori J.,Schleif, William A.

, p. 721 - 725 (2008/12/23)

A series of 4-oxo-4,5,6,7-tetrahydropyra...

Asymmetric hydrogenation of α-primary and secondary amino ketones: Efficient asymmetric syntheses of (-)-arbutamine and (-)-denopamine

Shang, Gao,Liu, Duan,Allen, Scott E.,Yang, Qin,Zhang, Xumu

, p. 7780 - 7784 (2008/04/03)

Two ss-receptor agonists (-)-denopamine ...

495-42-1 Process route

2-(methylamino)-1-phenylethan-1-one
35534-19-1

2-(methylamino)-1-phenylethan-1-one

(-)-Halostachine
495-42-1,6589-55-5

(-)-Halostachine

Conditions
Conditions Yield
With C30H29N2OP; iron(II) acetate; In tetrahydrofuran; at 25 ℃; for 1h; Reagent/catalyst; Inert atmosphere;
99%
(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol
291533-26-1

(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol

(-)-Halostachine
495-42-1,6589-55-5

(-)-Halostachine

Conditions
Conditions Yield
With hydrogenchloride; In diethyl ether; at 25 ℃; for 22h;
95%

495-42-1 Upstream products

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    (R)-(+)-<(2-methoxy-iso-propyl)oxy>benzeneacetonitrile

495-42-1 Downstream products

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    (R)-2-dimethylamino-1-phenyl-ethanol

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    (R)-2-(nitroso-methyl-amino)-1-phenyl-ethanol-(1)

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    84694-26-8

    2-phenyl>-3-methyl-5(R)-phenyloxazolidine

  • 157586-94-2
    157586-94-2

    (R)-3-Methyl-5-phenyl-[1,2,3]oxathiazolidine 2-oxide

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