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Bulk supply high purity Halostachin 495-42-1, Paid sample available
- Molecular Formula:C9H13NO
- Molecular Weight:151.208
- Melting Point:43-45°
- Boiling Point:244.1±7.0 °C(Predicted)
- PKA:14.03±0.20(Predicted)
- PSA:32.26000
- Density:1.036±0.06 g/cm3(Predicted)
- LogP:1.33030
Halostachin(Cas 495-42-1) Usage
|
General Description |
Halostachin, also known as 11α, 17α-dihydroxy-9α, 21, 21-trimethyl-19-nor-17β-pregna-1, 4-diene-3, 20-dione, is a synthetic glucocorticoid and a derivative of the natural hormone cortisone. It is used as a pharmaceutical agent for its anti-inflammatory and immunosuppressive properties, making it useful in the treatment of conditions such as asthma, allergic reactions, and autoimmune diseases. Halostachin works by inhibiting the production of inflammatory chemicals in the body, thereby reducing symptoms of inflammation. It is available in various dosage forms, including tablets, injections, and topical preparations, and is typically prescribed by healthcare professionals for short-term use due to its potential side effects and long-term risks. |
InChI:InChI=1S/C9H13NO/c1-10-7-9(11)8-5-3-2-4-6-8/h2-6,9-11H,7H2,1H3
495-42-1 Relevant articles
Method for synthesizing chiral alpha-amino alcohol compound
-
Paragraph 0026; 0030-0033; 0083-0092, (2021/07/28)
The invention discloses a method for syn...
AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS
-
Page/Page column 83; 84, (2016/07/05)
The present invention is related to amin...
Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors
Langford, H. Marie,Williams, Peter D.,Homnick, Carl F.,Vacca, Joseph P.,Felock, Peter J.,Stillmock, Kara A.,Witmer, Marc V.,Hazuda, Daria J.,Gabryelski, Lori J.,Schleif, William A.
, p. 721 - 725 (2008/12/23)
A series of 4-oxo-4,5,6,7-tetrahydropyra...
Asymmetric hydrogenation of α-primary and secondary amino ketones: Efficient asymmetric syntheses of (-)-arbutamine and (-)-denopamine
Shang, Gao,Liu, Duan,Allen, Scott E.,Yang, Qin,Zhang, Xumu
, p. 7780 - 7784 (2008/04/03)
Two ss-receptor agonists (-)-denopamine ...
495-42-1 Process route
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-
35534-19-1
2-(methylamino)-1-phenylethan-1-one
-
-
495-42-1,6589-55-5
(-)-Halostachine
| Conditions | Yield |
|---|---|
|
With
C30H29N2OP; iron(II) acetate;
In
tetrahydrofuran;
at 25 ℃;
for 1h;
Reagent/catalyst;
Inert atmosphere;
|
99% |
-
-
291533-26-1
(R)-2-[(tert-butoxycarbonyl)(methyl)amino]-1-phenylethanol
-
-
495-42-1,6589-55-5
(-)-Halostachine
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
diethyl ether;
at 25 ℃;
for 22h;
|
95% |
495-42-1 Upstream products
-
68579-60-2
2-(methylamino)-1-phenylethanol
-
131101-43-4
(4R,5R)-trans-5-phenyl-4-(p-tolylsulfonyl)-2-oxazoline
-
2019-72-9
N-methylamide of D-(-)-mandelic acid
-
142429-13-8
(R)-(+)-<(2-methoxy-iso-propyl)oxy>benzeneacetonitrile
495-42-1 Downstream products
-
34469-09-5
(R)-2-dimethylamino-1-phenyl-ethanol
-
36972-73-3
(R)-2-(nitroso-methyl-amino)-1-phenyl-ethanol-(1)
-
84694-26-8
2-
phenyl>-3-methyl-5(R)-phenyloxazolidine -
157586-94-2
(R)-3-Methyl-5-phenyl-[1,2,3]oxathiazolidine 2-oxide
